Alka-Seltzer®: Frequently Asked Questions


Here are answers to some of the most asked questions.

Effervescent tablets dissolve in water for fizzy, refreshing relief you can hear, see and feel. ReliefChews are delicious, chewy and portable. Both deliver fast relief. Learn more about our products here.

There are multiple advantages to using Alka-Seltzer effervescent products. In short: the medicine dissolves fast and goes to work instantly, neutralizing acid on contact. Because the medicines in Alka-Seltzer effervescents are in solution prior to ingestion, they do not require time to dissolve in the stomach like similar active ingredients taken in a tablet form.

Yes, a few. Effervescent comes in Regular flavor and Lemon-Lime. Flavors for ReliefChews are Tropical Punch and Assorted Fruit. Learn more about our products here.

All effervescent products contain anhydrous citric acid (antacid) and sodium bicarbonate (antacid). Alka-Seltzer Original, Extra Strength and Lemon-Lime also contain aspirin (analgesic). Alka-Seltzer Gold also contains potassium bicarbonate (antacid). Learn more about our products here.

ReliefChews contain calcium carbonate (antacid). Heartburn+Gas ReliefChews contain calcium carbonate (antacid) and simethicone (antigas).

Alka-Seltzer Original, Extra Strength and Lemon-Lime contain aspirin. The rest of our products do not.

No, none of the Alka-Seltzer formulas have ever contained PPA (phenylpropanolamine). PPA was removed from Alka-Seltzer Plus products in 2000.

The best temperature is room temperature. Cold water will slow down dissolution and warm water can make it foam excessively.

Alka-Seltzer contains citric acid and sodium bicarbonate (baking soda). When you drop the tablet in water, the acid and the baking soda react – this produces the fizz.

This is a sign that the tablets may have started to break down because there is an imperfection in the packaging. The product may not be effective. Call 1-800-986-0369.

Ask a Doctor or Pharmacist before use if you are taking a prescription medicine for diabetes.

We recommend that you discard any expired Alka-Seltzer product. It won’t be harmful if ingested, but it may not be as effective in relieving your symptoms.

As with any drug, if you are pregnant or breast-feeding, ask your health professional before using any Alka-Seltzer product.

The symptoms commonly referred to as a "hangover" aren't necessarily a result of excessive drinking. A single alcoholic drink is enough to trigger a hangover for some people, while others may drink heavily and escape the symptoms entirely.

Please read label directions to find out how long to use each Alka-Seltzer product.

Not exactly. Baking soda (sodium bicarbonate) does not contain anhydrous citric acid, the main active ingredient in Alka-Seltzer effervescent tablets that relieve heartburn and acid indigestion.

Alka-Seltzer products are available in most drug stores, food stores, mass merchandisers and club stores. If you do not find them on your local store shelf, ask the store manager to order them for you. We have found that most stores make their purchasing decisions based on consumer interest. to link to our product locator.

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